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Anti, a quiet English boy living in Quito, Ecuador, strikes up a friendship with flamboyant classmate Fabian, who is everything Anti isn't: handsome, athletic and popular. What's more, he lives with his rakish Uncle Suarez, while Anti is stuck in the dull ex-pat world inhabited by his parents. Suarez, a storyteller par excellence, infects the boys with his passion for outlandish tales, and before long their relationship becomes one conducted entirely through the medium of storytelling. One subject, however, is taboo: Fabian's parents. But when details surrounding their disappearance begin to emerge, Anti decides to console his friend with a story suggesting that Fabian's mother may be living at a bizarre hospital on the coast for patients with memory loss. With confused emotions and reality losing its tenuous grip, the boys embark on a quixotic voyage across Ecuador in search of an Amnesia Clinic that may, or may not exist.